Mechanochemical-Assisted Extraction of Active Alkaloids ...

12 MCAE , the response surface methodology was applied for 13 systematic investigation. The results showed that the highest yield of 14 alkaloids was obtained within 15 min of the total extraction time 15 under the optimal conditions: oxalic acid 20 wt %, 16 materials for 5 min, and the liquid/solid ratio of 20 mL/g.

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